InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GNAS

Summary

InnateDB Protein

IDBP-379652.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNAS

Protein Name

GNAS complex locus

Synonyms

AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PHP1A; PHP1B; PHP1C; POH;

Species

Homo sapiens

Ensembl Protein

ENSP00000412424

InnateDB Gene

IDBG-82827 (GNAS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	52 [view]
Protein-Protein	51 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000367 G-protein alpha subunit, group S
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR011025 G protein alpha subunit, helical insertion
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00503

PRINTS

PR00443
PR00318

PIRSF

SMART

SM00275

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt