Version 5.4
Homo sapiens Protein: WWC2
Summary
InnateDB Protein IDBP-380024.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WWC2
Protein Name WW and C2 domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000413521
InnateDB Gene IDBG-45849 (WWC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0032947 protein complex scaffold
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0035331 negative regulation of hippo signaling
GO:0046621 negative regulation of organ growth
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
PFAM PF00168
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6AWC2
PhosphoSite PhosphoSite-Q6AWC2
TrEMBL
UniProt Splice Variant
Entrez Gene 80014
UniGene Hs.715996
RefSeq
HUGO HGNC:24148
OMIM
CCDS
HPRD 12529
IMGT
EMBL AC019193 AC093844 AC099397 AJ566366 AK025682 AK074260 AK126057 AK127061 AL832424 BC017957 BC053873 BC107683 BX647378 BX647704
GenPept AAH17957 AAH53873 AAI07684 BAB15215 BAB85032 BAC86418 BAC86807 CAD97477 CAH10569 CAH10570 CAH10641

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca