InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GNAI1

Summary

InnateDB Protein

IDBP-380266.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNAI1

Protein Name

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1

Synonyms

Gi;

Species

Homo sapiens

Ensembl Protein

ENSP00000389435

InnateDB Gene

IDBG-23949 (GNAI1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.

Experimentally validated
Total	62 [view]
Protein-Protein	62 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR001408 G-protein alpha subunit, group I
IPR011025 G protein alpha subunit, helical insertion

PFAM

PF00503

PRINTS

PR00318
PR00441

PIRSF

SMART

SM00275

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt