Version 5.4
Homo sapiens Protein: SLCO4A1
Summary
InnateDB Protein IDBP-380360.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLCO4A1
Protein Name solute carrier organic anion transporter family, member 4A1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000414855
InnateDB Gene IDBG-85265 (SLCO4A1)
Protein Structure
UniProt Annotation
Function Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Ubiquitous, with the exception of spleen and leukocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR004156 Organic anion transporter polypeptide OATP
PFAM PF03137
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q96BD0
TrEMBL
UniProt Splice Variant
Entrez Gene 28231
UniGene Hs.235782
RefSeq
HUGO HGNC:10953
OMIM 612436
CCDS
HPRD 11582
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca