Version 5.4
Homo sapiens Protein: VCL
Summary
InnateDB Protein IDBP-380384.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VCL
Protein Name vinculin
Synonyms CMD1W; CMH15; HEL114; MV; MVCL;
Species Homo sapiens
Ensembl Protein ENSP00000415489
InnateDB Gene IDBG-78928 (VCL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 213 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 213 [view]
Protein-Protein 212 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR006077 Vinculin/alpha-catenin
IPR017997 Vinculin
PFAM PF01044
PRINTS PR00806
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5JQ13
UniProt Splice Variant
Entrez Gene 7414
UniGene Hs.643896
RefSeq
HUGO HGNC:12665
OMIM 193065
CCDS
HPRD 01900
IMGT
EMBL AL596247 AL731576
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca