InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GGCX

Summary

InnateDB Protein

IDBP-381605.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GGCX

Protein Name

gamma-glutamyl carboxylase

Synonyms

VKCFD1;

Species

Homo sapiens

Ensembl Protein

ENSP00000408045

InnateDB Gene

IDBG-59166 (GGCX)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008488	gamma-glutamyl carboxylase activity

Biological Process

GO:0006464	cellular protein modification process
GO:0007596	blood coagulation
GO:0017187	peptidyl-glutamic acid carboxylation
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR007782 Vitamin K-dependent gamma-carboxylase
IPR011020 HTTM
IPR011051 RmlC-like cupin domain

PFAM

PF05090

PRINTS

PIRSF

SMART

SM00752

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P38435

PhosphoSite

PhosphoSite-P38435

TrEMBL

UniProt Splice Variant

Entrez Gene

2677

UniGene

Hs.77719

RefSeq

NP_001135741

HUGO

HGNC:4247

OMIM

137167

CCDS

CCDS46353

HPRD

00665

IMGT

EMBL

AC016753 AK297397 BC013979 L17128 M81592 U65896

GenPept

AAA58643 AAA91834 AAB39832 AAH13979 AAY24340 BAG59837