InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PEX1

Summary

InnateDB Protein

IDBP-381815.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PEX1

Protein Name

peroxisomal biogenesis factor 1

Synonyms

PBD1A; PBD1B; ZWS; ZWS1;

Species

Homo sapiens

Ensembl Protein

ENSP00000410438

InnateDB Gene

IDBG-26608 (PEX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0009378	four-way junction helicase activity
GO:0042623	ATPase activity, coupled

Biological Process

GO:0006200	ATP catabolic process
GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0006625	protein targeting to peroxisome

Cellular Component

GO:0005778	peroxisomal membrane
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal
IPR009010 Aspartate decarboxylase-like domain
IPR015343 Peroxisome biogenesis factor 1, alpha/beta
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF05496
PF09263

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite