Version 5.4
Homo sapiens Protein: CBLB
Summary
InnateDB Protein IDBP-382029.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CBLB
Protein Name Cas-Br-M (murine) ecotropic retroviral transforming sequence b
Synonyms Cbl-b; RNF56;
Species Homo sapiens
Ensembl Protein ENSP00000393906
InnateDB Gene IDBG-48442 (CBLB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 79 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 79 [view]
Protein-Protein 79 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001784 phosphotyrosine binding
GO:0004842 ubiquitin-protein transferase activity
GO:0004871 signal transducer activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003153 Adaptor protein Cbl, N-terminal helical
PFAM PF02262
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JU85
UniProt Splice Variant
Entrez Gene 868
UniGene Hs.622985
RefSeq
HUGO HGNC:1542
OMIM 604491
CCDS
HPRD 05136
IMGT
EMBL AC016138 AC112485 AC126185
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca