InnateDB Protein
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IDBP-382670.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CASP5
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Protein Name
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caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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ICE(rel)III; ICEREL-III; ICH-3;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000398130
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InnateDB Gene
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IDBG-69591 (CASP5)
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Protein Structure
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|
Function |
Mediator of programmed cell death (apoptosis).
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004197
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cysteine-type endopeptidase activity
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GO:0008234
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cysteine-type peptidase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001309
Peptidase C14, ICE, catalytic subunit p20
IPR002138
Peptidase C14, caspase non-catalytic subunit p10
IPR011600
Peptidase C14, caspase domain
IPR015917
Peptidase C14A, caspase precursor p45, core
|
PFAM |
PF00656
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PRINTS |
PR00376
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PIRSF |
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SMART |
SM00115
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TIGRFAMs |
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Modification |
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SwissProt |
P51878
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PhosphoSite |
PhosphoSite-P51878
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
838
|
UniGene |
Hs.213327
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RefSeq |
NP_001129582
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HUGO |
HGNC:1506
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OMIM |
602665
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CCDS |
CCDS44718
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HPRD |
04048
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IMGT |
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EMBL |
AK296660
AP001153
BC074994
BC113406
CH471065
DQ228672
DQ228673
DQ228674
DQ228676
DQ228677
DQ508420
U28015
X94993
|
GenPept |
AAA75172
AAH74994
AAI13407
ABB58698
ABB58699
ABB58700
ABB58702
ABB58703
ABF47103
BAG59257
CAA64450
EAW67054
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