Version 5.4
Homo sapiens Protein: MUTYH
Summary
InnateDB Protein IDBP-383146.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MUTYH
Protein Name mutY homolog (E. coli)
Synonyms MYH;
Species Homo sapiens
Ensembl Protein ENSP00000410263
InnateDB Gene IDBG-97893 (MUTYH)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003265 HhH-GPD domain
IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif
IPR011257 DNA glycosylase
PFAM PF00730
PF10576
PRINTS
PIRSF
SMART SM00478
SM00525
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5T418
UniProt Splice Variant
Entrez Gene 4595
UniGene Hs.271353
RefSeq
HUGO HGNC:7527
OMIM 604933
CCDS
HPRD 05380
IMGT
EMBL AL359540
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca