InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IRAK1

Summary

InnateDB Protein

IDBP-383283.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IRAK1

Protein Name

interleukin-1 receptor-associated kinase 1

Synonyms

IRAK; pelle;

Species

Homo sapiens

Ensembl Protein

ENSP00000410953

InnateDB Gene

IDBG-90782 (IRAK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 196 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.

Experimentally validated
Total	196 [view]
Protein-Protein	190 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	2 [view]
DNA-RNA	0

Predicted by orthology
Total	33 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0045087

innate immune response (InnateDB)

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR011009 Protein kinase-like domain

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

3654

UniGene

Hs.522819

RefSeq

HUGO

HGNC:6112

OMIM

300283

CCDS

HPRD

02235

IMGT

EMBL

GenPept