Version 5.4
Homo sapiens Protein: SPIB
Summary
InnateDB Protein IDBP-383801.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPIB
Protein Name Spi-B transcription factor (Spi-1/PU.1 related)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000391877
InnateDB Gene IDBG-64473 (SPIB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0030154 cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000418 Ets domain
PFAM PF00178
PRINTS PR00454
PIRSF
SMART SM00413
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q01892
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 6689
UniGene
RefSeq NP_001230927
HUGO HGNC:11242
OMIM 606802
CCDS CCDS58674
HPRD
IMGT
EMBL AC020909 AK292644 AK300639 BC007921 CH471135 X66079 X96998
GenPept AAH07921 BAF85333 BAG62328 CAA46878 CAA65726 EAW71858

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca