Version 5.4
Homo sapiens Protein: ARMC10
Summary
InnateDB Protein IDBP-384482.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARMC10
Protein Name armadillo repeat containing 10
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000413619
InnateDB Gene IDBG-34112 (ARMC10)
Protein Structure
UniProt Annotation
Function May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53. {ECO:0000269PubMed:12839973, ECO:0000269PubMed:17904127}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:12839973}; Single-pass membrane protein {ECO:0000269PubMed:12839973}.
Disease Associations
Tissue Specificity Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain. {ECO:0000269PubMed:12839973}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0040008 regulation of growth
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006911 Armadillo repeat-containing domain
IPR016024 Armadillo-type fold
PFAM PF04826
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N2F6
PhosphoSite PhosphoSite-Q8N2F6
TrEMBL
UniProt Splice Variant
Entrez Gene 83787
UniGene Hs.729929
RefSeq NP_001154481
HUGO HGNC:21706
OMIM 611864
CCDS CCDS55146
HPRD 18133
IMGT
EMBL AC007683 AC073127 AC108167 AK075500 AK291818 AK301565 AY150851 AY150852 AY150853 AY150854 BC003586
GenPept AAH03586 AAN72313 AAN72314 AAN72315 AAN72316 AAS07456 AAS07482 AAS07531 BAC11655 BAF84507 BAG63060

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca