Version 5.4
Homo sapiens Protein: IL1B
Summary
InnateDB Protein IDBP-384827.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL1B
Protein Name interleukin 1, beta
Synonyms IL-1; IL1-BETA; IL1F2;
Species Homo sapiens
Ensembl Protein ENSP00000407219
InnateDB Gene IDBG-66519 (IL1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 53 [view]
Protein-Protein 29 [view]
Protein-DNA 21 [view]
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005149 interleukin-1 receptor binding
Biological Process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003294 Interleukin-1 alpha/beta
IPR003502 Interleukin-1 propeptide
IPR008996 Cytokine, IL-1-like
PFAM PF02394
PRINTS PR01357
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JWV2
UniProt Splice Variant
Entrez Gene 3553
UniGene Hs.700961
RefSeq
HUGO HGNC:5992
OMIM 147720
CCDS
HPRD 00985
IMGT
EMBL AC079753
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca