Version 5.4
Homo sapiens Protein: DAB1
Summary
InnateDB Protein IDBP-384959.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DAB1
Protein Name disabled homolog 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000395296
InnateDB Gene IDBG-99165 (DAB1)
Protein Structure
UniProt Annotation
Function Adapter molecule functioning in neural development. May regulate SIAH1 activity (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006020 PTB/PI domain
PFAM PF00640
PF14719
PRINTS
PIRSF
SMART SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75553
PhosphoSite PhosphoSite-O75553
TrEMBL X6R4J9
UniProt Splice Variant
Entrez Gene 1600
UniGene Hs.595239
RefSeq
HUGO HGNC:2661
OMIM 603448
CCDS
HPRD 04582
IMGT
EMBL AB210012 AC104464 AF071062 AF263547 AF525763 AK095513 AL080278 AL109845 AL109944 AL137855 AL139219 AL161740 AL354883 AL355004 AL357373 AL359739 AL365187 AL365367 AL390243 AL391826 AL442223 AL445193 AL627090 AL663085 BC067445 BC067446 BC067447 BC112938 CH471059
GenPept AAC70068 AAF73058 AAH67445 AAH67446 AAH67447 AAI12939 AAM83107 BAE06094 BAG53075 CAI18815 CAI18816 CAI18817 CAI19217 CAI19218 CAI19219 CAI19220 CAI19221 CAI22360 CAI22361 CAI22362 CAI22363 CAI22364 EAX06637

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca