Version 5.4
Homo sapiens Protein: ECT2
Summary
InnateDB Protein IDBP-385486.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ECT2
Protein Name epithelial cell transforming sequence 2 oncogene
Synonyms ARHGEF31;
Species Homo sapiens
Ensembl Protein ENSP00000403501
InnateDB Gene IDBG-65239 (ECT2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 151 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 151 [view]
Protein-Protein 151 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
Biological Process
GO:0000902 cell morphogenesis
GO:0000910 cytokinesis
GO:0043547 positive regulation of GTPase activity
GO:0045666 positive regulation of neuron differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001357 BRCT domain
PFAM PF00533
PF12738
PRINTS
PIRSF
SMART SM00292
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JDB4
UniProt Splice Variant
Entrez Gene 1894
UniGene Hs.741516
RefSeq
HUGO HGNC:3155
OMIM 600586
CCDS
HPRD 11860
IMGT
EMBL AC108667
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca