InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTPRZ1

Summary

InnateDB Protein

IDBP-385854.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPRZ1

Protein Name

protein tyrosine phosphatase, receptor-type, Z polypeptide 1

Synonyms

HPTPZ; HPTPzeta; phosphacan; PTP-ZETA; PTP18; PTPRZ; PTPZ; R-PTP-zeta-2; RPTPB; RPTPbeta;

Species

Homo sapiens

Ensembl Protein

ENSP00000410000

InnateDB Gene

IDBG-38364 (PTPRZ1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0007417	central nervous system development
GO:0007611	learning or memory
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation
GO:0048709	oligodendrocyte differentiation
GO:0070445	regulation of oligodendrocyte progenitor proliferation

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR001148 Alpha carbonic anhydrase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR003961 Fibronectin, type III
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00194
PF00041
PF01108

PRINTS

PR00700

PIRSF

SMART

SM00194
SM01057
SM00404
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt