InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FGF12

Summary

InnateDB Protein

IDBP-386666.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FGF12

Protein Name

fibroblast growth factor 12

Synonyms

FGF12B; FHF1;

Species

Homo sapiens

Ensembl Protein

ENSP00000397635

InnateDB Gene

IDBG-69854 (FGF12)

Protein Structure

UniProt Annotation

Function

Probably involved in nervous system development and function.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008083	growth factor activity
GO:0008201	heparin binding
GO:0017080	sodium channel regulator activity
GO:0044325	ion channel binding

Biological Process

GO:0007165	signal transduction
GO:0007254	JNK cascade
GO:0007267	cell-cell signaling
GO:0007399	nervous system development
GO:0007507	heart development
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0086002	cardiac muscle cell action potential involved in contraction
GO:1902305	regulation of sodium ion transmembrane transport
GO:2000649	regulation of sodium ion transmembrane transporter activity