Version 5.4
Homo sapiens Protein: DNTTIP2
Summary
InnateDB Protein IDBP-386878.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNTTIP2
Protein Name deoxynucleotidyltransferase, terminal, interacting protein 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000411010
InnateDB Gene IDBG-100352 (DNTTIP2)
Protein Structure
UniProt Annotation
Function Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein. {ECO:0000269PubMed:12786946, ECO:0000269PubMed:15047147}.
Subcellular Localization Nucleus {ECO:0000269PubMed:12786946, ECO:0000269PubMed:15047147}.
Disease Associations
Tissue Specificity Widely expressed with higher levels in testis. {ECO:0000269PubMed:12786946, ECO:0000269PubMed:15047147}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR014810 Fcf2 pre-rRNA processing
PFAM PF08698
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5QJE6
PhosphoSite PhosphoSite-Q5QJE6
TrEMBL
UniProt Splice Variant
Entrez Gene 30836
UniGene Hs.85769
RefSeq NP_055412
HUGO HGNC:24013
OMIM 611199
CCDS CCDS44174
HPRD 09994
IMGT
EMBL AB046574 AK222722 AK292379 AL049796 AY336729 AY394925 BC047688 BC130622 CH471097 U15552
GenPept AAA50601 AAH47688 AAI30623 AAQ95169 AAR02407 BAD08331 BAD96442 BAF85068 CAI21812 EAW73064

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca