Version 5.4
Homo sapiens Protein: FAP
Summary
InnateDB Protein IDBP-387028.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAP
Protein Name fibroblast activation protein, alpha
Synonyms DPPIV; FAPA;
Species Homo sapiens
Ensembl Protein ENSP00000411391
InnateDB Gene IDBG-73736 (FAP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
IPR002469 Peptidase S9B, dipeptidylpeptidase IV N-terminal
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00326
PF00930
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DLR2
UniProt Splice Variant
Entrez Gene 2191
UniGene Hs.654370
RefSeq NP_001278736
HUGO HGNC:3590
OMIM 600403
CCDS
HPRD 02674
IMGT
EMBL AC007750 AK297118
GenPept BAG59624

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca