Version 5.4
Homo sapiens Protein: SCN2A
Summary
InnateDB Protein IDBP-387162.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCN2A
Protein Name sodium channel, voltage-gated, type II, alpha subunit
Synonyms BFIC3; BFIS3; BFNIS; EIEE11; HBA; HBSCI; HBSCII; Na(v)1.2; NAC2; Nav1.2; SCN2A1; SCN2A2;
Species Homo sapiens
Ensembl Protein ENSP00000406454
InnateDB Gene IDBG-74003 (SCN2A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005248 voltage-gated sodium channel activity
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR005821 Ion transport domain
PFAM PF00520
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8T7W7
UniProt Splice Variant
Entrez Gene 6326
UniGene Hs.93485
RefSeq
HUGO HGNC:10588
OMIM 182390
CCDS
HPRD 03133
IMGT
EMBL AC011303 AC013438 AK289656 HQ726798
GenPept AEJ07965 BAF82345

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca