Version 5.4
Homo sapiens Protein: ECT2L
Summary
InnateDB Protein IDBP-387512.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ECT2L
Protein Name epithelial cell transforming sequence 2 oncogene-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000387388
InnateDB Gene IDBG-97097 (ECT2L)
Protein Structure
UniProt Annotation
Function May act as a guanine nucleotide exchange factor (GEF). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR001810 F-box domain
PFAM PF00621
PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00325
SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q008S8
PhosphoSite PhosphoSite-Q008S8
TrEMBL B7ZBI6
UniProt Splice Variant
Entrez Gene 345930
UniGene Hs.660603
RefSeq
HUGO HGNC:21118
OMIM
CCDS CCDS43508
HPRD
IMGT
EMBL AL121834 BC146884 DQ904331
GenPept AAI46885 ABI98401 CAI42871

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca