Version 5.4
Homo sapiens Protein: SHH
Summary
InnateDB Protein IDBP-387542.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHH
Protein Name sonic hedgehog
Synonyms HHG1; HLP3; HPE3; MCOPCB5; SMMCI; TPT; TPTPS;
Species Homo sapiens
Ensembl Protein ENSP00000413871
InnateDB Gene IDBG-50464 (SHH)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007267 cell-cell signaling
GO:0007275 multicellular organismal development
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000320 Hedgehog, N-terminal signalling domain
IPR001657 Hedgehog protein
IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain
PFAM PF01085
PRINTS PR00632
PIRSF PIRSF009400
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8WEH4
UniProt Splice Variant
Entrez Gene 6469
UniGene Hs.738995
RefSeq
HUGO HGNC:10848
OMIM 600725
CCDS
HPRD 02838
IMGT
EMBL AC078834
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca