InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STAT1

Summary

InnateDB Protein

IDBP-388069.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STAT1

Protein Name

signal transducer and activator of transcription 1, 91kDa

Synonyms

CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91;

Species

Homo sapiens

Ensembl Protein

ENSP00000402548

InnateDB Gene

IDBG-77617 (STAT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 332 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	332 [view]
Protein-Protein	235 [view]
Protein-DNA	95 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR013799 STAT transcription factor, protein interaction
IPR013800 STAT transcription factor, all-alpha
IPR015988 STAT transcription factor, coiled coil

PFAM

PF02865
PF01017

PRINTS

PIRSF

SMART

SM00964

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite