Version 5.4
Homo sapiens Protein: NDUFS1
Summary
InnateDB Protein IDBP-388561.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDUFS1
Protein Name NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Synonyms CI-75k; CI-75Kd; PRO1304;
Species Homo sapiens
Ensembl Protein ENSP00000389413
InnateDB Gene IDBG-79438 (NDUFS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 47 [view]
Protein-Protein 44 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0009055 electron carrier activity
GO:0016491 oxidoreductase activity
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:0055114 oxidation-reduction process
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001041 2Fe-2S ferredoxin-type domain
IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
PFAM PF00111
PF10588
PRINTS
PIRSF
SMART SM00929
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JPQ5
UniProt Splice Variant
Entrez Gene 4719
UniGene Hs.598436
RefSeq
HUGO HGNC:7707
OMIM 157655
CCDS
HPRD 01145
IMGT
EMBL AC007383
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca