Version 5.4
Homo sapiens Protein: TNS1
Summary
InnateDB Protein IDBP-388844.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNS1
Protein Name tensin 1
Synonyms MST091; MST122; MST127; MSTP122; MSTP127; MXRA6; PPP1R155; TNS;
Species Homo sapiens
Ensembl Protein ENSP00000405460
InnateDB Gene IDBG-80769 (TNS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 16 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR014020 Tensin phosphatase, C2 domain
IPR029021 Protein-tyrosine phosphatase-like
IPR029023 Tensin phosphatase, lipid phosphatase domain
PFAM PF00168
PF00130
PF10409
PRINTS PR00360
PIRSF
SMART SM00239
SM00109
SM00404
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7ERH1
UniProt Splice Variant
Entrez Gene 7145
UniGene Hs.663032
RefSeq
HUGO HGNC:11973
OMIM 600076
CCDS
HPRD 02512
IMGT
EMBL AC009469 AC010136
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca