InnateDB Protein
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IDBP-3991.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NIPA2
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Protein Name
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non imprinted in Prader-Willi/Angelman syndrome 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000337618
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InnateDB Gene
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IDBG-3989 (NIPA2)
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Protein Structure
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Function |
Acts as a selective Mg(2+) transporter. {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Early endosome {ECO:0000250}. Note=Recruited to the cell membrane in response to low extracellular magnesium. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. {ECO:0000269PubMed:14508708}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0015095
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magnesium ion transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000620
Drug/metabolite transporter
IPR008521
Magnesium transporter NIPA
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PFAM |
PF00892
PF05653
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N8Q9
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PhosphoSite |
PhosphoSite-Q8N8Q9
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TrEMBL |
H0YMQ7
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UniProt Splice Variant |
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Entrez Gene |
81614
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UniGene |
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RefSeq |
NP_112184
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HUGO |
HGNC:17044
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OMIM |
608146
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CCDS |
CCDS73693
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HPRD |
16290
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IMGT |
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EMBL |
AC011767
AK096305
AK300843
AY732242
BC000957
BC011775
BK001120
CH471258
CR606982
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GenPept |
AAH00957
AAH11775
AAU34000
BAC04757
BAG62494
DAA01509
EAW65552
EAW65553
EAW65554
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