InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CILP2

Summary

InnateDB Protein

IDBP-39999.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CILP2

Protein Name

cartilage intermediate layer protein 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000291495

InnateDB Gene

IDBG-39997 (CILP2)

Protein Structure

UniProt Annotation

Function

May play a role in cartilage scaffolding. {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in articular chondrocytes but not in knee meniscal cartilage cells. {ECO:0000269PubMed:12746903}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000884 Thrombospondin, type 1 repeat
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR008969 Carboxypeptidase-like, regulatory domain
IPR013098 Immunoglobulin I-set
IPR013784 Carbohydrate-binding-like fold

PFAM

PF00090
PF07679

PRINTS

PIRSF

SMART

SM00209
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8IUL8