Version 5.4
| Mus musculus Protein: Mtmr4 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-400098.4 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Mtmr4 | ||||||||
| Protein Name | myotubularin related protein 4 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000112902 | ||||||||
| InnateDB Gene | IDBG-207495 (Mtmr4) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Localized to perinuclear region. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2180699 | ||||||||
| InterPro |
IPR000306
FYVE zinc finger IPR000387 Protein-tyrosine/Dual specificity phosphatase IPR010569 Myotubularin-like phosphatase domain IPR011011 Zinc finger, FYVE/PHD-type IPR017455 Zinc finger, FYVE-related IPR029021 Protein-tyrosine phosphatase-like |
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| PFAM |
PF01363
PF06602 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00064
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q91XS1 | ||||||||
| PhosphoSite | PhosphoSite-Q91XS1 | ||||||||
| TrEMBL | A7M7R1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 170749 | ||||||||
| UniGene | Mm.489088 | ||||||||
| RefSeq | |||||||||
| MGI ID | |||||||||
| MGI Symbol | Mtmr4 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS25214 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF262986 AK146641 AL596086 | ||||||||
| GenPept | AAK58180 BAE27324 CAI35136 CAI35138 | ||||||||