Version 5.4
Mus musculus Protein: Tbc1d10b
Summary
InnateDB Protein IDBP-400204.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d10b
Protein Name TBC1 domain family, member 10b
Synonyms 1110003P22Rik; C87963;
Species Mus musculus
Ensembl Protein ENSMUSP00000113307
InnateDB Gene IDBG-210078 (Tbc1d10b)
Protein Structure
UniProt Annotation
Function Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1915699
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BHL3
PhosphoSite PhosphoSite-Q8BHL3
TrEMBL
UniProt Splice Variant
Entrez Gene 68449
UniGene Mm.443832
RefSeq NP_653105
MGI ID
MGI Symbol Tbc1d10b
OMIM
CCDS CCDS40139
HPRD
IMGT
EMBL AC122537 AF285112 AK047320 AK047327 BC025889 BC072576
GenPept AAH25889 AAH72576 AAK82984 BAC33022 BAC33025

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca