InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aasdh

Summary

InnateDB Protein

IDBP-400768.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aasdh

Protein Name

aminoadipate-semialdehyde dehydrogenase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113792

InnateDB Gene

IDBG-173517 (Aasdh)

Protein Structure

UniProt Annotation

Function

Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA (By similarity). Putative 2-aminoadipic 6-semialdehyde dehydrogenase, which may be involved in lysine catabolism. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003824	catalytic activity
GO:0004043	L-aminoadipate-semialdehyde dehydrogenase activity
GO:0005524	ATP binding
GO:0016878	acid-thiol ligase activity

Biological Process

GO:0006631	fatty acid metabolic process
GO:0008150	biological_process
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:2442517

InterPro

IPR000873 AMP-dependent synthetase/ligase
IPR009081 Acyl carrier protein-like
IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat

PFAM

PF00501
PF00550

PRINTS

PIRSF

SMART

SM00564

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q80WC9