Version 5.4
Mus musculus Protein: Lmtk3
Summary
InnateDB Protein IDBP-400770.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lmtk3
Protein Name lemur tyrosine kinase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000112592
InnateDB Gene IDBG-184349 (Lmtk3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305PubMed:17651901}; Single-pass membrane protein {ECO:0000305PubMed:17651901}. Cell projection, axon {ECO:0000269PubMed:17651901}. Cell projection, dendrite {ECO:0000269PubMed:17651901}. Note=Punctate pattern in cell projections.
Disease Associations
Tissue Specificity Expressed in brain. Predominantly expressed in the cerebellum and hippocampal formation (at protein level). {ECO:0000269PubMed:17651901}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0010923 negative regulation of phosphatase activity
GO:0018108 peptidyl-tyrosine phosphorylation
Cellular Component
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0030425 dendrite
Protein Structure and Domains
PDB ID MGI:3039582
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF07714
PRINTS PR00109
PIRSF
SMART SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5XJV6
PhosphoSite PhosphoSite-Q5XJV6
TrEMBL D3Z7K7
UniProt Splice Variant
Entrez Gene 381983
UniGene Mm.44928
RefSeq NP_001277919
MGI ID
MGI Symbol Lmtk3
OMIM
CCDS CCDS39961
HPRD
IMGT
EMBL AB288873 AC149053 AC167242 BC083185 BC094377
GenPept AAH83185 AAH94377 BAF64834

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca