InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igfbp2

Summary

InnateDB Protein

IDBP-401103.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igfbp2

Protein Name

insulin-like growth factor binding protein 2

Synonyms

AI255832; IBP-2; Igfbp-2; mIGFBP-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112706

InnateDB Gene

IDBG-166043 (Igfbp2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005520	insulin-like growth factor binding
GO:0031994	insulin-like growth factor I binding
GO:0031995	insulin-like growth factor II binding

Biological Process

GO:0007165	signal transduction
GO:0007565	female pregnancy
GO:0007568	aging
GO:0007584	response to nutrient
GO:0009612	response to mechanical stimulus
GO:0010226	response to lithium ion
GO:0032355	response to estradiol
GO:0032526	response to retinoic acid
GO:0032870	cellular response to hormone stimulus
GO:0042104	positive regulation of activated T cell proliferation
GO:0042493	response to drug
GO:0051384	response to glucocorticoid

Cellular Component

GO:0005615	extracellular space
GO:0016324	apical plasma membrane
GO:0031410	cytoplasmic vesicle

Protein Structure and Domains

PDB ID

MGI:96437

InterPro

IPR000716 Thyroglobulin type-1
IPR012210 Insulin-like growth factor binding protein 2
IPR022321 Insulin-like growth factor-binding protein family 1-6, chordata

PFAM

PF00086

PRINTS

PR01978
PR01976

PIRSF

SMART

SM00211

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YU40

UniProt Splice Variant

Entrez Gene

16008

UniGene

RefSeq

XP_006495770

MGI ID

MGI Symbol

Igfbp2

OMIM

CCDS

HPRD

IMGT

EMBL

AC115870 AC121498

GenPept