InnateDB Protein
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IDBP-401302.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Lman1
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Protein Name
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lectin, mannose-binding, 1
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Synonyms
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2610020P13Rik; AI326273; AU043785; C730041J05; ERGIC53; F5F8D; gp58; MCFD1; MR60; P58;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000113326
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InnateDB Gene
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IDBG-154877 (Lman1)
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Protein Structure
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Function |
Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
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Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
30 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1917611
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InterPro |
IPR005052
Legume-like lectin
IPR008985
Concanavalin A-like lectin/glucanases superfamily
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PFAM |
PF03388
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D0F3
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PhosphoSite |
PhosphoSite-Q9D0F3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
70361
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UniGene |
Mm.408877
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RefSeq |
NP_001165533
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MGI ID |
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MGI Symbol |
Lman1
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OMIM |
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CCDS |
CCDS29313
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HPRD |
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IMGT |
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EMBL |
AK011495
BC057165
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GenPept |
AAH57165
BAB27655
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