InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CNPY2

Summary

InnateDB Protein

IDBP-40701.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CNPY2

Protein Name

canopy 2 homolog (zebrafish)

Synonyms

HP10390; MSAP; TMEM4; ZSIG9;

Species

Homo sapiens

Ensembl Protein

ENSP00000273308

InnateDB Gene

IDBG-547092 (CNPY2)

Protein Structure

UniProt Annotation

Function

Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.

Subcellular Localization

Endoplasmic reticulum {ECO:0000255PROSITE- ProRule:PRU10138}.

Disease Associations

Tissue Specificity

Expressed in different tissues. Highest levels are detected in adult placenta, liver and pancreas. {ECO:0000269PubMed:12826659}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	4 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0010629	negative regulation of gene expression
GO:0010988	regulation of low-density lipoprotein particle clearance
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process