InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD82

Summary

InnateDB Protein

IDBP-40875.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD82

Protein Name

CD82 molecule

Synonyms

4F9; C33; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27;

Species

Homo sapiens

Ensembl Protein

ENSP00000227155

InnateDB Gene

IDBG-40873 (CD82)

Protein Structure

UniProt Annotation

Function

Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Lymphoid specific.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.

Experimentally validated
Total	34 [view]
Protein-Protein	23 [view]
Protein-DNA	11 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin

PFAM

PF00335

PRINTS

PR00259

PIRSF

PIRSF002419

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P27701

PhosphoSite

PhosphoSite-P27701

TrEMBL

E9PP61

UniProt Splice Variant

Entrez Gene

3732

UniGene

Hs.527778

RefSeq

NP_002222

HUGO

HGNC:6210

OMIM

600623

CCDS

CCDS7909

HPRD

09004

IMGT

EMBL

AC010768 AY303776 BC000726 BC001821 CH471064 CR542255 S48196 U20770 U67268 U67269 U67270 U67271 U67272 U67273 U67274 X53795

GenPept

AAB23825 AAC50133 AAC51205 AAH00726 AAH01821 AAP76181 CAA37804 CAG47051 EAW68063 EAW68064