InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: METTL1

Summary

InnateDB Protein

IDBP-43849.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

METTL1

Protein Name

methyltransferase like 1

Synonyms

C12orf1; TRM8; TRMT8; YDL201w;

Species

Homo sapiens

Ensembl Protein

ENSP00000257848

InnateDB Gene

IDBG-43845 (METTL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.

Experimentally validated
Total	37 [view]
Protein-Protein	35 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0005515	protein binding
GO:0008176	tRNA (guanine-N7-)-methyltransferase activity

Biological Process

GO:0006400	tRNA modification
GO:0030488	tRNA methylation
GO:0036265	RNA (guanine-N7)-methylation

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UBP6

PhosphoSite

PhosphoSite-Q9UBP6

TrEMBL

F8VSD9

UniProt Splice Variant

Entrez Gene

4234

UniGene

RefSeq

NP_075422

HUGO

HGNC:7030

OMIM

604466

CCDS

CCDS8956

HPRD

06834

IMGT

EMBL

AC025165 AK223202 AK314851 BC000550 X96698 Y18642 Y18643

GenPept

AAH00550 BAD96922 BAG37368 CAA65470 CAA77238 CAA77239