Version 5.4
| Homo sapiens Protein: CLDN22 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-45938.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CLDN22 | ||||||||
| Protein Name | claudin 22 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000318113 | ||||||||
| InnateDB Gene | IDBG-45936 (CLDN22) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. | ||||||||
| Subcellular Localization | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR004031
PMP-22/EMP/MP20/Claudin superfamily IPR006187 Claudin |
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| PFAM |
PF00822
PF13903 |
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| PRINTS |
PR01077
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8N7P3 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 53842 | ||||||||
| UniGene | |||||||||
| RefSeq | NP_001104789 | ||||||||
| HUGO | HGNC:2044 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS43286 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC093844 AK098064 | ||||||||
| GenPept | |||||||||