InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TNIP1

Summary

InnateDB Protein

IDBP-473389.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNIP1

Protein Name

TNFAIP3 interacting protein 1

Synonyms

ABIN-1; NAF1; nip40-1; VAN;

Species

Homo sapiens

Ensembl Protein

ENSP00000429912

InnateDB Gene

IDBG-54098 (TNIP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	63 [view]
Protein-Protein	57 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004843	ubiquitin-specific protease activity
GO:0005488	binding
GO:0005515	protein binding
GO:0051019	mitogen-activated protein kinase binding

Biological Process

GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0006412	translation
GO:0006952	defense response
GO:0006954	inflammatory response
GO:0007159	leukocyte cell-cell adhesion
GO:0009101	glycoprotein biosynthetic process
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045071	negative regulation of viral genome replication
GO:0045087	innate immune response (InnateDB)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050729	positive regulation of inflammatory response
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:0085032	modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade