InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SMG7

Summary

InnateDB Protein

IDBP-473420.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMG7

Protein Name

smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Synonyms

C1orf16; EST1C; SGA56M;

Species

Homo sapiens

Ensembl Protein

ENSP00000425133

InnateDB Gene

IDBG-105301 (SMG7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0051721	protein phosphatase 2A binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006406	mRNA export from nucleus
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0035303	regulation of dephosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0045111	intermediate filament cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR019458 Telomerase activating protein Est1

PFAM

PF10374

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q92540

PhosphoSite

PhosphoSite-Q92540

TrEMBL

Q96N31

UniProt Splice Variant

Entrez Gene

9887

UniGene

RefSeq

NP_963863

HUGO

HGNC:16792

OMIM

610964

CCDS

CCDS41445

HPRD

10723

IMGT

EMBL

AB085674 AK056035 AK299178 AL137800 AL355387 AL359876 AL449223 BC036381 BC052565 D87437

GenPept

AAH36381 AAH52565 BAA13381 BAB71079 BAC53621 BAG61224 CAI16627 CAI19486