Homo sapiens Protein: HMGCS1
Summary
InnateDB Protein IDBP-474023.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMGCS1
Protein Name 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Synonyms HMGCS;
Species Homo sapiens
Ensembl Protein ENSP00000427339
InnateDB Gene IDBG-19361 (HMGCS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004421 hydroxymethylglutaryl-CoA synthase activity
Biological Process
GO:0008152 metabolic process
GO:0008299 isoprenoid biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
IPR016039 Thiolase-like
PFAM PF01154
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RIW1
UniProt Splice Variant
Entrez Gene 3157
UniGene Hs.602526
RefSeq
HUGO HGNC:5007
OMIM 142940
CCDS
HPRD 07515
IMGT
EMBL AC114947
GenPept