InnateDB Protein
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IDBP-474362.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IDO1
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Protein Name
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indoleamine 2,3-dioxygenase 1
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Synonyms
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IDO; IDO-1; INDO;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000430505
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InnateDB Gene
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IDBG-18750 (IDO1)
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Protein Structure
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|
Function |
Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen. {ECO:0000269PubMed:17671174}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
5
[view]
|
Protein-DNA |
3
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
8 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000898
Indoleamine 2,3-dioxygenase
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PFAM |
PF01231
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P14902
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PhosphoSite |
PhosphoSite-P14902
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TrEMBL |
E5RIX2
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UniProt Splice Variant |
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Entrez Gene |
3620
|
UniGene |
Hs.738619
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RefSeq |
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HUGO |
HGNC:6059
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OMIM |
147435
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CCDS |
CCDS47847
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HPRD |
00935
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IMGT |
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EMBL |
AC007991
AK313259
AY221100
BC027882
M34455
M86472
M86473
M86474
M86475
M86476
M86477
M86478
M86479
M86480
M86481
X17668
|
GenPept |
AAA36081
AAH27882
AAO34405
BAG36069
CAA35663
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