InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: POLK

Summary

InnateDB Protein

IDBP-474551.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

POLK

Protein Name

polymerase (DNA directed) kappa

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000423532

InnateDB Gene

IDBG-29209 (POLK)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	19 [view]
Protein-Protein	19 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003684	damaged DNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0046872	metal ion binding

Biological Process

GO:0006261	DNA-dependent DNA replication
GO:0006281	DNA repair
GO:0006297	nucleotide-excision repair, DNA gap filling

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001126 DNA-repair protein, UmuC-like
IPR017961 DNA polymerase, Y-family, little finger domain
IPR017963 DNA-repair protein, UmuC-like, N-terminal
IPR024728 DNA polymerase type-Y, HhH motif

PFAM

PF00817
PF11799
PF11798

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UBT6

PhosphoSite