Version 5.4
Homo sapiens Protein: ATR
Summary
InnateDB Protein IDBP-475367.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATR
Protein Name ataxia telangiectasia and Rad3 related
Synonyms FCTCS; FRP1; MEC1; SCKL; SCKL1;
Species Homo sapiens
Ensembl Protein ENSP00000422553
InnateDB Gene IDBG-59521 (ATR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 125 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 125 [view]
Protein-Protein 121 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0008152 metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR011009 Protein kinase-like domain
PFAM PF00454
PRINTS
PIRSF
SMART SM00146
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0Y8Y6
UniProt Splice Variant
Entrez Gene 545
UniGene Hs.271791
RefSeq
HUGO HGNC:882
OMIM 601215
CCDS
HPRD 08369
IMGT
EMBL AC109992 AC134509
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca