Version 5.4
Homo sapiens Protein: RTEL1
Summary
InnateDB Protein IDBP-475738.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RTEL1
Protein Name Regulator of telomere elongation helicase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000425576
InnateDB Gene IDBG-544022 (RTEL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0000723 telomere maintenance
GO:0006200 ATP catabolic process
GO:0006281 DNA repair
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0032508 DNA duplex unwinding
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NZ71
PhosphoSite PhosphoSite-Q9NZ71
TrEMBL
UniProt Splice Variant
Entrez Gene 51750
UniGene Hs.743461
RefSeq
HUGO HGNC:15888
OMIM 608833
CCDS
HPRD 15281
IMGT
EMBL AB029011 AF217795 AF217796 AK000485 AK299332 AK302508 AK304798 AL080127 AL353715 CH471077
GenPept AAF33687 AAF35243 BAA83040 BAA91197 BAG61337 BAG63785 BAG65548 CAB45725 EAW75238 EAW75239 EAW75240 EAW75241 EAW75245

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca