InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UBE2H

Summary

InnateDB Protein

IDBP-476593.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UBE2H

Protein Name

ubiquitin-conjugating enzyme E2H

Synonyms

E2-20K; GID3; UBC8; UBCH; UBCH2;

Species

Homo sapiens

Ensembl Protein

ENSP00000419097

InnateDB Gene

IDBG-40928 (UBE2H)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.

Experimentally validated
Total	80 [view]
Protein-Protein	79 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016881	acid-amino acid ligase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0070936	protein K48-linked ubiquitination
GO:0070979	protein K11-linked ubiquitination

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000608 Ubiquitin-conjugating enzyme, E2
IPR016135 Ubiquitin-conjugating enzyme/RWD-like

PFAM

PF00179

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P62256

PhosphoSite

PhosphoSite-P62256

TrEMBL

UniProt Splice Variant

Entrez Gene

7328

UniGene

Hs.717847

RefSeq

NP_874356

HUGO

HGNC:12484

OMIM

601082

CCDS

CCDS47710

HPRD

03052

IMGT

EMBL

AC073320 AC084865 AY302138 BC006277 BT006756 CH236950 CH471070 Z29328 Z29330 Z29331

GenPept

AAH06277 AAP35402 AAP57630 CAA82525 CAA82527 CAA82528 EAL24099 EAW83736