Version 5.4
Homo sapiens Protein: KPNA1
Summary
InnateDB Protein IDBP-476667.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KPNA1
Protein Name karyopherin alpha 1 (importin alpha 5)
Synonyms IPOA5; NPI-1; RCH2; SRP1;
Species Homo sapiens
Ensembl Protein ENSP00000419890
InnateDB Gene IDBG-52534 (KPNA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 86 [view]
Protein-Protein 86 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0006606 protein import into nucleus
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000225 Armadillo
IPR000357 HEAT
IPR002652 Importin-alpha, importin-beta-binding domain
IPR016024 Armadillo-type fold
PFAM PF00514
PF02985
PF01749
PRINTS
PIRSF
SMART SM00185
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JYI4
UniProt Splice Variant
Entrez Gene 3836
UniGene Hs.610402
RefSeq
HUGO HGNC:6394
OMIM 600686
CCDS
HPRD 02819
IMGT
EMBL AC083798 AC096861
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca