Version 5.4
Homo sapiens Protein: SCLT1
Summary
InnateDB Protein IDBP-477878.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCLT1
Protein Name sodium channel and clathrin linker 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000420861
InnateDB Gene IDBG-37917 (SCLT1)
Protein Structure
UniProt Annotation
Function Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:23348840}. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042384 cilium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0015630 microtubule cytoskeleton
GO:0070062 extracellular vesicular exosome
GO:0097539 ciliary transition fiber
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96NL6
PhosphoSite PhosphoSite-Q96NL6
TrEMBL D6RDM2
UniProt Splice Variant
Entrez Gene 132320
UniGene Hs.654690
RefSeq NP_001287826
HUGO HGNC:26406
OMIM 611399
CCDS
HPRD 08700
IMGT
EMBL AC093783 AC093826 AK055217 BC064428 BC121057 BC121058 BC128051 CH471056
GenPept AAH64428 AAI21058 AAI21059 AAI28052 BAB70876 EAX05167

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca