Version 5.4
Homo sapiens Protein: RRP1
Summary
InnateDB Protein IDBP-478580.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RRP1
Protein Name ribosomal RNA processing 1 homolog (S. cerevisiae)
Synonyms D21S2056E; NNP-1; NOP52; RRP1A;
Species Homo sapiens
Ensembl Protein ENSP00000417464
InnateDB Gene IDBG-4897 (RRP1)
Protein Structure
UniProt Annotation
Function Plays a critical role in the generation of 28S rRNA.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:12429849, ECO:0000269PubMed:9192856}.
Disease Associations
Tissue Specificity Ubiquitously expressed in fetal and adult tissues. {ECO:0000269PubMed:9192856}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030688 preribosome, small subunit precursor
Protein Structure and Domains
PDB ID
InterPro IPR010301 Nucleolar, Nop52
PFAM PF05997
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P56182
PhosphoSite PhosphoSite-P56182
TrEMBL
UniProt Splice Variant
Entrez Gene 8568
UniGene Hs.110757
RefSeq NP_003674
HUGO HGNC:18785
OMIM 610653
CCDS CCDS42951
HPRD 10857
IMGT
EMBL AL137757 AP001752 BC000380 U79775
GenPept AAC51625 AAH00380 BAA95542 CAB70909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca