Homo sapiens Protein: NOS3
Summary
InnateDB Protein IDBP-479143.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOS3
Protein Name nitric oxide synthase 3 (endothelial cell)
Synonyms ECNOS; eNOS;
Species Homo sapiens
Ensembl Protein ENSP00000420551
InnateDB Gene IDBG-48571 (NOS3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
Experimentally validated
Total 69 [view]
Protein-Protein 69 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004517 nitric-oxide synthase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0006809 nitric oxide biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001094 Flavodoxin
IPR004030 Nitric oxide synthase, N-terminal
IPR008254 Flavodoxin/nitric oxide synthase
IPR029039 Flavoprotein-like
PFAM PF02898
PF00258
PRINTS PR00369
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q96P37
UniProt Splice Variant
Entrez Gene 4846
UniGene Hs.716846
RefSeq NP_001153582
HUGO HGNC:7876
OMIM 163729
CCDS CCDS55183
HPRD 01224
IMGT
EMBL AF032908 AF387340 AF415200
GenPept AAB87083 AAK71989 AAL07497